Erratum to: nab-Paclitaxel Plus Gemcitabine Versus Gemcitabine in Patients with Metastatic Pancreatic Adenocarcinoma: Canadian Subgroup Analysis of the Phase 3 MPACT Trial
نویسندگان
چکیده
The authors would like to correct the errors in Table 1 and text in the published article. The correct table and the text should read as below. In Table 1, the numbers for the intent-to-treat population for biliary stent and previous Whipple procedure were erroneously switched. Table 1 should appear as below. The corresponding text for Table 1 under the Baseline Characteristics heading in the Results section should read, ‘‘Fewer patients in the Canadian cohort had a KPS of 100 than in the ITT population,’’ i.e., removing ‘‘or previous Whipple procedure’’ from the original sentence which read ‘‘Fewer patients in the Canadian cohort had a KPS of 100 or previous Whipple procedure than in the ITT population.’’ Under the Statistical Analyses section, the second-to-last sentence reads ‘‘A nonstratified log-rank test was PFS between the treatment arms, and the HR and two-sided 95% CIs were estimated by a Cox proportional hazards model.’’ It should read ‘‘A stratified log-rank test was used to compare PFS between the treatment arms, and the HR and two-sided 95% CIs were estimated by a Cox proportional hazards model.’’ In the Discussion (last paragraph beginning at the bottom of page 756), the sentence reads, ‘‘Health Canada has approved nab-P ? Gem and FOLFIRINOX for the treatment of patients with The online version of the original article can be found under doi:10.1007/s12325-016-0327-4.
منابع مشابه
Tumor Reduction in Primary and Metastatic Pancreatic Cancer Lesions With nab-Paclitaxel and Gemcitabine
OBJECTIVES Results from the phase 3 Metastatic Pancreatic Adenocarcinoma Clinical Trial (MPACT) led to approval of nab-paclitaxel plus gemcitabine for first-line treatment of metastatic pancreatic cancer. The current analysis evaluated the effects of nab-paclitaxel plus gemcitabine versus gemcitabine on primary pancreatic and metastatic lesions. METHODS In this analysis of the previously desc...
متن کاملnab-Paclitaxel Plus Gemcitabine Versus Gemcitabine in Patients with Metastatic Pancreatic Adenocarcinoma: Canadian Subgroup Analysis of the Phase 3 MPACT Trial
INTRODUCTION The phase III MPACT trial in patients with metastatic pancreatic cancer (MPC) demonstrated superior efficacy of nab-paclitaxel (nab-P) plus gemcitabine (Gem) compared with Gem monotherapy, including the primary endpoint of overall survival (OS; median 8.7 vs. 6.6 months; hazard ratio [HR] 0.72; P < 0.001). A significant treatment difference favoring nab-P + Gem over Gem was observe...
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PURPOSE The global Phase III MPACT trial demonstrated superior efficacy of nab-paclitaxel plus gemcitabine over gemcitabine alone as first-line treatment for metastatic pancreatic cancer. Region was a randomization stratification factor in the MPACT trial. This subgroup analysis of MPACT examined efficacy and safety of patients treated in Western Europe. PATIENTS AND METHODS Patients received...
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